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Cocaine-taking and cocaine-seeking behaviors in rats remain stable after systemic administration of GYKI 52466, a non-competitive AMPA receptor antagonist
Given the posited role of enhanced AMPA-mediated synaptic transmission in relapse to drug seeking, we investigated whether the systemic administration of AMPA receptor antagonist GYKI 52466 inhibits cocaine-taking and cocaine-seeking behavior in rats. Rats were trained to self-administer cocaine unt...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3267379/ https://ncbi.nlm.nih.gov/pubmed/22206835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2011.12.028 |
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