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Cocaine-taking and cocaine-seeking behaviors in rats remain stable after systemic administration of GYKI 52466, a non-competitive AMPA receptor antagonist

Given the posited role of enhanced AMPA-mediated synaptic transmission in relapse to drug seeking, we investigated whether the systemic administration of AMPA receptor antagonist GYKI 52466 inhibits cocaine-taking and cocaine-seeking behavior in rats. Rats were trained to self-administer cocaine unt...

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Detalhes bibliográficos
Main Authors: Srivastava, Ratika, Xi, Zheng-Xiong, Gardner, Eliot L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267379/
https://ncbi.nlm.nih.gov/pubmed/22206835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2011.12.028
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