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Treatment of early and late kainic acid-induced status epilepticus with the noncompetitive AMPA receptor antagonist GYKI 52466
PURPOSE: Benzodiazepines such as diazepam may fail to effectively treat status epilepticus because benzodiazepine-sensitive GABA(A) receptors are progressively internalized with continued seizure activity. Ionotropic glutamate receptors, including AMPA receptors, are externalized, so that AMPA recep...
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| Publicado no: | Epilepsia |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4535693/ https://ncbi.nlm.nih.gov/pubmed/19682025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2009.02205.x |
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