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Negative Allosteric Modulation of AMPA‐preferring Receptors by the Selective Isomer GYKI 53784 (LY303070), a Specific Non‐competitive AMPA Antagonist

GYKI 53784 or LY303070 [(–)1‐(4‐aminophenyl)‐4‐methyl‐7,8‐methylenedioxy‐4,5‐dihydro‐3‐methylcarbamoyl‐2,3‐benzodiazepine] belongs to a new family of 2,3‐benzodiazepine compounds (also called homophtalazines) selective and non‐competitive antagonists at α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazole‐propion...

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Detalhes bibliográficos
Publicado no:CNS Drug Rev
Main Authors: Ruel, Jérôme, Guitton, Matthieu J., Puel, Jean‐Luc
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741693/
https://ncbi.nlm.nih.gov/pubmed/12353057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2002.tb00227.x
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