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Structural analysis of human 2′-O-ribose methyltransferases involved in mRNA cap structure formation
The 5′ cap of human messenger RNA contains 2′-O-methylation of the first and often second transcribed nucleotide that is important for its processing, translation and stability. Human enzymes that methylate these nucleotides, termed CMTr1 and CMTr2, respectively, have recently been identified. Howev...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Pub. Group
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3941023/ https://ncbi.nlm.nih.gov/pubmed/24402442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4004 |
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