Structural analysis of human 2′-O-ribose methyltransferases involved in mRNA cap structure formation

The 5′ cap of human messenger RNA contains 2′-O-methylation of the first and often second transcribed nucleotide that is important for its processing, translation and stability. Human enzymes that methylate these nucleotides, termed CMTr1 and CMTr2, respectively, have recently been identified. Howev...

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Bibliografiske detaljer
Main Authors: Smietanski, Miroslaw, Werner, Maria, Purta, Elzbieta, Kaminska, Katarzyna H., Stepinski, Janusz, Darzynkiewicz, Edward, Nowotny, Marcin, Bujnicki, Janusz M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941023/
https://ncbi.nlm.nih.gov/pubmed/24402442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4004
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