Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases

BACKGROUND: SPOUT methyltransferases (MTases) are a large class of S-adenosyl-L-methionine-dependent enzymes that exhibit an unusual alpha/beta fold with a very deep topological knot. In 2001, when no crystal structures were available for any of these proteins, Anantharaman, Koonin, and Aravind iden...

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Bibliografske podrobnosti
Main Authors: Tkaczuk, Karolina L, Dunin-Horkawicz, Stanislaw, Purta, Elzbieta, Bujnicki, Janusz M
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829167/
https://ncbi.nlm.nih.gov/pubmed/17338813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-73
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