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Conversion of Azides into Diazo Compounds in Water

Diazo compounds are in widespread use in synthetic organic chemistry, but have untapped potential in chemical biology. We report on the design and optimization of a phosphinoester that mediates the efficient conversion of azides into diazo compounds in phosphate buffer at neutral pH and room tempera...

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Detalhes bibliográficos
Main Authors: Chou, Ho-Hsuan, Raines, Ronald T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940534/
https://ncbi.nlm.nih.gov/pubmed/24053717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja407822b
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