Preferential and specific binding of human αB-crystallin to cataract-related variant of γS-crystallin

Transparency in the eye lens is maintained via specific, functional interactions among the structural βγ- and chaperone α-crystallins. Here we report the structure and α-crystallin binding interface of the G18V variant of human γS-crystallin (γS-G18V), which is linked to hereditary childhood-onset c...

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Bibliografische gegevens
Hoofdauteurs: Kingsley, Carolyn N., Brubaker, William D., Markovic, Stefan, Diehl, Anne, Brindley, Amanda J., Oschkinat, Hartmut, Martin, Rachel W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940334/
https://ncbi.nlm.nih.gov/pubmed/24183572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.09.017
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