Novel complex MAD phasing and RNase H structural insights using selenium oligonucleotides

The crystal structures of protein–nucleic acid complexes are commonly determined using selenium-derivatized proteins via MAD or SAD phasing. Here, the first protein–nucleic acid complex structure determined using selenium-derivatized nucleic acids is reported. The RNase H–RNA/DNA complex is used as...

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Bibliografiske detaljer
Main Authors: Abdur, Rob, Gerlits, Oksana O., Gan, Jianhua, Jiang, Jiansheng, Salon, Jozef, Kovalevsky, Andrey Y., Chumanevich, Alexander A., Weber, Irene T., Huang, Zhen
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2014
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940196/
https://ncbi.nlm.nih.gov/pubmed/24531469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004713027922
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