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H-Ras forms dimers on membrane surfaces via a protein–protein interface
The lipid-anchored small GTPase Ras is an important signaling node in mammalian cells. A number of observations suggest that Ras is laterally organized within the cell membrane, and this may play a regulatory role in its activation. Lipid anchors composed of palmitoyl and farnesyl moieties in H-, N-...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3939930/ https://ncbi.nlm.nih.gov/pubmed/24516166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321155111 |
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