One-way membrane trafficking of SOS in receptor-triggered Ras activation

SOS is a key activator of the small GTPase Ras. In cells, SOS-Ras signaling is thought to be initiated predominantly by membrane-recruitment of SOS via the adaptor Grb2 and balanced by rapidly reversible Grb2:SOS binding kinetics. However, SOS has multiple protein and lipid interactions that provide...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Christensen, Sune M., Tu, Hsiung-Lin, Jun, Jesse E., Alvarez, Steven, Triplet, Meredith G., Iwig, Jeffrey S., Yadav, Kamlesh K., Bar-Sagi, Dafna, Roose, Jeroen P., Groves, Jay T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016256/
https://ncbi.nlm.nih.gov/pubmed/27501536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3275
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados