Resveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention

Tetraploidy constitutes a genomically metastable state that can lead to aneuploidy and genomic instability. Tetraploid cells are frequently found in preneoplastic lesions, including intestinal cancers arising due to the inactivation of the tumor suppressor adenomatous polyposis coli (APC). Using a p...

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Détails bibliographiques
Auteurs principaux: Lissa, Delphine, Senovilla, Laura, Rello-Varona, Santiago, Vitale, Ilio, Michaud, Mickaël, Pietrocola, Federico, Boilève, Alice, Obrist, Florine, Bordenave, Chloé, Garcia, Pauline, Michels, Judith, Jemaà, Mohamed, Kepp, Oliver, Castedo, Maria, Kroemer, Guido
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2014
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939868/
https://ncbi.nlm.nih.gov/pubmed/24516128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318440111
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