Resveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention

Tetraploidy constitutes a genomically metastable state that can lead to aneuploidy and genomic instability. Tetraploid cells are frequently found in preneoplastic lesions, including intestinal cancers arising due to the inactivation of the tumor suppressor adenomatous polyposis coli (APC). Using a p...

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Detalhes bibliográficos
Main Authors: Lissa, Delphine, Senovilla, Laura, Rello-Varona, Santiago, Vitale, Ilio, Michaud, Mickaël, Pietrocola, Federico, Boilève, Alice, Obrist, Florine, Bordenave, Chloé, Garcia, Pauline, Michels, Judith, Jemaà, Mohamed, Kepp, Oliver, Castedo, Maria, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939868/
https://ncbi.nlm.nih.gov/pubmed/24516128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318440111
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