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Inhibition of post-translational N-glycosylation by HRD1 that controls the fate of ABCG5/8 transporter
N-glycosylation of proteins in endoplasmic reticulum is critical for protein quality control. We showed here a post-translational N-glycosylation affected by the HRD1 E3 ubiquitin ligase. Both WT- and E3-defective C329S-HRD1 decreased the level of high mannose form of ABCG8, a protein that heterodim...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3939451/ https://ncbi.nlm.nih.gov/pubmed/24584735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04258 |
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