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Inhibitors of Human ABCG2: From Technical Background to Recent Updates With Clinical Implications

The ATP-binding cassette transporter G2 (ABCG2; also known as breast cancer resistance protein, BCRP) has been suggested to be involved in clinical multidrug resistance (MDR) in cancer like other ABC transporters such as ABCB1 (P-glycoprotein). As an efflux pump exhibiting a broad substrate specific...

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書目詳細資料
發表在:Front Pharmacol
Main Authors: Toyoda, Yu, Takada, Tappei, Suzuki, Hiroshi
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2019
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411714/
https://ncbi.nlm.nih.gov/pubmed/30890942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00208
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