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Inhibitors of Human ABCG2: From Technical Background to Recent Updates With Clinical Implications
The ATP-binding cassette transporter G2 (ABCG2; also known as breast cancer resistance protein, BCRP) has been suggested to be involved in clinical multidrug resistance (MDR) in cancer like other ABC transporters such as ABCB1 (P-glycoprotein). As an efflux pump exhibiting a broad substrate specific...
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| Publicado no: | Front Pharmacol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6411714/ https://ncbi.nlm.nih.gov/pubmed/30890942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00208 |
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