Lack of Z-DNA conformation in mitomycin-modified polynucleotides having inverted circular dichroism.

Poly(dG-dC) . poly(dG-dC) and Micrococcus lysodeikticus DNA were modified by exposure to reductively activated mitomycin C, an antitumor antibiotic. The resulting covalent drug-polynucleotide complexes displayed varying degrees of CD inversions, which are strikingly similar to the inverted spectrum...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Tomasz, M, Barton, J K, Magliozzo, C C, Tucker, D, Lafer, E M, Stollar, B D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1983
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC393935/
https://ncbi.nlm.nih.gov/pubmed/6574457
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi