Lack of Z-DNA conformation in mitomycin-modified polynucleotides having inverted circular dichroism.

Poly(dG-dC) . poly(dG-dC) and Micrococcus lysodeikticus DNA were modified by exposure to reductively activated mitomycin C, an antitumor antibiotic. The resulting covalent drug-polynucleotide complexes displayed varying degrees of CD inversions, which are strikingly similar to the inverted spectrum...

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Detaylı Bibliyografya
Asıl Yazarlar: Tomasz, M, Barton, J K, Magliozzo, C C, Tucker, D, Lafer, E M, Stollar, B D
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1983
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC393935/
https://ncbi.nlm.nih.gov/pubmed/6574457
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