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Caspase-mediated activation of Caenorhabditis elegans CED-8 promotes apoptosis and phosphatidylserine externalisation

During apoptosis, phosphatidylserine (PS), normally restricted to the inner leaflet of the plasma membrane, is exposed on the surface of apoptotic cells and serves as an “eat-me” signal to trigger phagocytosis. It is poorly understood how PS exposure is activated in apoptotic cells. Here we report t...

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Autors principals: Chen, Yu-Zen, Mapes, James, Lee, Eui-Seung, Skeen-Gaar, Riley Robert, Xue, Ding
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939056/
https://ncbi.nlm.nih.gov/pubmed/24225442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3726
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