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CED-1, CED-7, and TTR-52 act in a pathway to regulate exoplasmic phosphatidylserine expression on apoptotic and phagocytic cells

BACKGROUND: Phosphatidylserine (PS) normally confined to the cytoplasmic leaflet of plasma membrane (PM) is externalized to the exoplasmic leaflet (exPS) during apoptosis where it serves as an “eat-me” signal to phagocytes. In addition, some living cells such as macrophages also express exPS. RESULT...

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Main Authors: Mapes, James, Chen, Yu-Zen, Kim, Anna, Mitani, Shohei, Kang, Byung-Ho, Xue, Ding
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816170/
https://ncbi.nlm.nih.gov/pubmed/22727702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.05.052
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