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Conjugation of Vitamin E Analog α-TOS to Pt(IV) Complexes for Dual-Targeting Anticancer Therapy
We report two platinum(IV) complexes conjugated with a vitamin E analog, α-tocopherol succinate (α-TOS). One of the conjugates displays the activity of both cisplatin and αTOS in cancer cells, causing damage to DNA and mitochondria simultaneously. Accordingly, it serves as promising dual-targeting a...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3938893/ https://ncbi.nlm.nih.gov/pubmed/24452361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc48740g |
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