Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis

Glioblastoma (GBM) is the most aggressive form of primary brain tumour, with dismal patient outcome. Treatment failure is associated with intrinsic or acquired apoptosis resistance and the presence of a highly tumourigenic subpopulation of cancer cells called GBM stem cells. Tumour necrosis factor-r...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Murphy, Á. C., Weyhenmeyer, B., Noonan, J., Kilbride, S. M., Schimansky, S., Loh, K. P., Kögel, D., Letai, A. G., Prehn, J. H. M., Murphy, B. M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer US 2013
Pynciau:
Original Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938842/
https://ncbi.nlm.nih.gov/pubmed/24213561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-013-0935-2
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