Inhibition of Hepatitis C Virus Infection by DNA Aptamer against NS2 Protein

NS2 protein is essential for hepatitis C virus (HCV) replication. NS2 protein was expressed and purified. Aptamers against NS2 protein were raised and antiviral effects of the aptamers were examined. The molecular mechanism through which the aptamers exert their anti-HCV activity was investigated. T...

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Bibliografske podrobnosti
Main Authors: Gao, Yimin, Yu, Xiaoyan, Xue, Binbin, Zhou, Fei, Wang, Xiaohong, Yang, Darong, Liu, Nianli, Xu, Li, Fang, Xiaohong, Zhu, Haizhen
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938669/
https://ncbi.nlm.nih.gov/pubmed/24587329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090333
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