Inhibition of Hepatitis C Virus Infection by DNA Aptamer against Envelope Protein

Hepatitis C virus (HCV) envelope protein (E1E2) is essential for virus binding to host cells. Aptamers have been demonstrated to have strong promising applications in drug development. In the current study, a cDNA fragment encoding the entire E1E2 gene of HCV was cloned. E1E2 protein was expressed a...

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Detalhes bibliográficos
Main Authors: Yang, Darong, Meng, Xianghe, Yu, Qinqin, Xu, Li, Long, Ying, Liu, Bin, Fang, Xiaohong, Zhu, Haizhen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811438/
https://ncbi.nlm.nih.gov/pubmed/23877701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00897-13
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