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Inhibition of Hepatitis C Virus Infection by DNA Aptamer against NS2 Protein

NS2 protein is essential for hepatitis C virus (HCV) replication. NS2 protein was expressed and purified. Aptamers against NS2 protein were raised and antiviral effects of the aptamers were examined. The molecular mechanism through which the aptamers exert their anti-HCV activity was investigated. T...

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Detalhes bibliográficos
Main Authors: Gao, Yimin, Yu, Xiaoyan, Xue, Binbin, Zhou, Fei, Wang, Xiaohong, Yang, Darong, Liu, Nianli, Xu, Li, Fang, Xiaohong, Zhu, Haizhen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938669/
https://ncbi.nlm.nih.gov/pubmed/24587329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090333
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