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2-Octynoic Acid Inhibits Hepatitis C Virus Infection through Activation of AMP-Activated Protein Kinase

Many chronic hepatitis C virus (HCV)-infected patients with current therapy do not clear the virus. It is necessary to find novel treatments. The effect of 2-octynoic acid (2-OA) on HCV infection in human hepatocytes was examined. The mechanism of 2-OA antiviral activity was explored. Our data showe...

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Detalhes bibliográficos
Main Authors: Yang, Darong, Xue, Binbin, Wang, Xiaohong, Yu, Xiaoyan, Liu, Nianli, Gao, Yimin, Liu, Chen, Zhu, Haizhen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669134/
https://ncbi.nlm.nih.gov/pubmed/23741428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064932
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