Chargement en cours...

Isolation and expression of an altered mouse dihydrofolate reductase cDNA.

We have constructed a cDNA library from a murine cell line expressing high levels of a dihydrofolate reductase (tetrahydrofolate dehydrogenase; 5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase, EC 1.5.1.3) that displays an abnormally low affinity for methotrexate. From this library we have isolated a c...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Simonsen, C C, Levinson, A D
Format: Artigo
Langue:Inglês
Publié: 1983
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC393852/
https://ncbi.nlm.nih.gov/pubmed/6573667
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!