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Cell cycle regulation of dihydrofolate reductase mRNA metabolism in mouse fibroblasts.

We have used the technique of DNA-excess filter hybridization to measure directly the content and metabolism of the mRNA for dihydrofolate reductase (DHFR; 5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase, EC 1.5.1.3). The studies were conducted with a methotrexate-resistant derivative of mouse 3T6 fib...

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Autors principals: Hendrickson, S L, Wu, J S, Johnson, L F
Format: Artigo
Idioma:Inglês
Publicat: 1980
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC350012/
https://ncbi.nlm.nih.gov/pubmed/6933549
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