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Structure-guided Inhibitor Design Expands the Scope of Analog-Sensitive Kinase Technology
Engineered analog-sensitive (AS) protein kinases have emerged as powerful tools for dissecting phospho-signaling pathways, for elucidating the cellular function of individual kinases, and for deciphering unanticipated effects of clinical therapeutics. A crucial and necessary feature of this technolo...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3938192/ https://ncbi.nlm.nih.gov/pubmed/23841803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400376p |
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