Chargement en cours...
Construction of conditional analog-sensitive kinase alleles in the fission yeast Schizosaccharomyces pombe
Reversible protein phosphorylation is a major regulatory mechanism in a cell. A chemical-genetic strategy to conditionally inactivate protein kinases has been developed recently. Mutating a single residue in the ATP-binding pocket confers sensitivity to small-molecule inhibitors. The inhibitor can o...
Enregistré dans:
| Auteurs principaux: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2007
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2957860/ https://ncbi.nlm.nih.gov/pubmed/18007635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2007.447 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|