A Redox-Dependent Mechanism for Regulation of AMPK Activation by Thioredoxin1 during Energy Starvation

5'-AMP-activated protein kinase (AMPK) is a key regulator of metabolism and survival during energy stress. Dysregulation of AMPK is strongly associated with oxidative stress-related disease. However, whether and how AMPK is regulated by intracellular redox status remains unknown. Here we show t...

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Bibliographic Details
Main Authors: Shao, Dan, Oka, Shin-ichi, Liu, Tong, Zhai, Peiyong, Ago, Tetsuro, Sciarretta, Sebastiano, Li, Hong, Sadoshima, Junichi
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937768/
https://ncbi.nlm.nih.gov/pubmed/24506865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.12.013
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