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Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy through Upregulation of miR-98/let-7

RATIONALE: Thioredoxin 1 (Trx1) inhibits pathological cardiac hypertrophy. MicroRNAs (miRNAs) are small non-coding RNAs that downregulate posttranscriptional expression of target molecules. OBJECTIVES: We investigated the role of miRNAs in mediating the anti-hypertrophic effect of Trx1 upon angioten...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yang, Yanfei, Ago, Tetsuro, Zhai, Peiyong, Abdellatif, Maha, Sadoshima, Junichi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249645/
https://ncbi.nlm.nih.gov/pubmed/21183740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.228437
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