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Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy through Upregulation of miR-98/let-7
RATIONALE: Thioredoxin 1 (Trx1) inhibits pathological cardiac hypertrophy. MicroRNAs (miRNAs) are small non-coding RNAs that downregulate posttranscriptional expression of target molecules. OBJECTIVES: We investigated the role of miRNAs in mediating the anti-hypertrophic effect of Trx1 upon angioten...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3249645/ https://ncbi.nlm.nih.gov/pubmed/21183740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.228437 |
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