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A Redox-Dependent Mechanism for Regulation of AMPK Activation by Thioredoxin1 during Energy Starvation
5'-AMP-activated protein kinase (AMPK) is a key regulator of metabolism and survival during energy stress. Dysregulation of AMPK is strongly associated with oxidative stress-related disease. However, whether and how AMPK is regulated by intracellular redox status remains unknown. Here we show t...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937768/ https://ncbi.nlm.nih.gov/pubmed/24506865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.12.013 |
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