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Structural Basis of Regulation of von Willebrand Factor Binding to Glycoprotein Ib
Activation by elongational flow of von Willebrand factor (VWF) is critical for primary hemostasis. Mutations causing type 2B von Willebrand disease (VWD), platelet-type VWD (PT-VWD), and tensile force each increase affinity of the VWF A1 domain and platelet glycoprotein Ibα (GPIbα) for one another;...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937634/ https://ncbi.nlm.nih.gov/pubmed/24391089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.511220 |
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