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Serglycin Proteoglycan Is Required for Multiple Myeloma Cell Adhesion, in Vivo Growth, and Vascularization

Recently, it was discovered that serglycin, a hematopoietic cell proteoglycan, is the major proteoglycan expressed and constitutively secreted by multiple myeloma (MM) cells. High levels of serglycin are present in the bone marrow aspirates of at least 30% of newly diagnosed MM patients. However, it...

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Detalhes bibliográficos
Main Authors: Purushothaman, Anurag, Toole, Bryan P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937626/
https://ncbi.nlm.nih.gov/pubmed/24403068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.532143
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