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Lack of an Efficient Endoplasmic Reticulum-localized Recycling System Protects Peroxiredoxin IV from Hyperoxidation

Typical 2-Cys peroxiredoxins are required to remove hydrogen peroxide from several different cellular compartments. Their activity can be regulated by hyperoxidation and consequent inactivation of the active-site peroxidatic cysteine. Here we developed a simple assay to quantify the hyperoxidation o...

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Detalhes bibliográficos
Main Authors: Cao, Zhenbo, Subramaniam, Suraj, Bulleid, Neil J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937625/
https://ncbi.nlm.nih.gov/pubmed/24403061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.529305
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