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Recycling of peroxiredoxin IV provides a novel pathway for disulphide formation in the endoplasmic reticulum

Disulphide formation in the endoplasmic reticulum (ER) is catalysed by members of the protein disulphide isomerase (PDI) family. These enzymes can be oxidized by the flavoprotein ER oxidoreductin 1 (Ero1), which couples disulphide formation with reduction of oxygen to form hydrogen peroxide (H(2)O(2...

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Autors principals: Tavender, Timothy J, Springate, Jennifer J, Bulleid, Neil J
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018787/
https://ncbi.nlm.nih.gov/pubmed/21057456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.273
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