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Recycling of peroxiredoxin IV provides a novel pathway for disulphide formation in the endoplasmic reticulum
Disulphide formation in the endoplasmic reticulum (ER) is catalysed by members of the protein disulphide isomerase (PDI) family. These enzymes can be oxidized by the flavoprotein ER oxidoreductin 1 (Ero1), which couples disulphide formation with reduction of oxygen to form hydrogen peroxide (H(2)O(2...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018787/ https://ncbi.nlm.nih.gov/pubmed/21057456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.273 |
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