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Crystal Structure of Reduced and of Oxidized Peroxiredoxin IV Enzyme Reveals a Stable Oxidized Decamer and a Non-disulfide-bonded Intermediate in the Catalytic Cycle

Peroxiredoxin IV (PrxIV) is an endoplasmic reticulum-localized enzyme that metabolizes the hydrogen peroxide produced by endoplasmic reticulum oxidase 1 (Ero1). It has been shown to play a role in de novo disulfide formation, oxidizing members of the protein disulfide isomerase family of enzymes, an...

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Xehetasun bibliografikoak
Egile Nagusiak: Cao, Zhenbo, Tavender, Timothy J., Roszak, Aleksander W., Cogdell, Richard J., Bulleid, Neil J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234919/
https://ncbi.nlm.nih.gov/pubmed/21994946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.298810
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