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Rapamycin Prevents Epilepsy in a Mouse Model of Tuberous Sclerosis Complex
OBJECTIVE: Tuberous Sclerosis Complex (TSC) represents one of the most common genetic causes of epilepsy. TSC gene inactivation leads to hyperactivation of the mammalian target of rapamycin (mTOR) signaling pathway, raising the intriguing possibility that mTOR inhibitors might be effective in preven...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937593/ https://ncbi.nlm.nih.gov/pubmed/18389497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21331 |
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