Cross-Presentation of Synthetic Long Peptides by Human Dendritic Cells: A Process Dependent on ERAD Component p97/VCP but Not sec61 and/or Derlin-1

Antitumor vaccination using synthetic long peptides (SLP) is an additional therapeutic strategy currently under development. It aims to activate tumor-specific CD8(+) CTL by professional APCs such as DCs. DCs can activate T lymphocytes by MHC class I presentation of exogenous antigens - a process re...

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Detalhes bibliográficos
Main Authors: Ménager, Jérémie, Ebstein, Frédéric, Oger, Romain, Hulin, Philippe, Nedellec, Steven, Duverger, Eric, Lehmann, Andrea, Kloetzel, Peter-Michael, Jotereau, Francine, Guilloux, Yannick
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937416/
https://ncbi.nlm.nih.gov/pubmed/24587108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089897
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