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Genome-wide RNAi screen identifies SEC61A and VCP as conserved regulators of Sindbis virus entry
Alphaviruses are a large class of insect-borne human pathogens and little is known about the host factor requirements for infection. To identify such factors we performed a genome-wide RNAi screen using model Drosophila cells and validated 94 genes that impacted infection of Sindbis virus (SINV), th...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3920290/ https://ncbi.nlm.nih.gov/pubmed/24332855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.11.028 |
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