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Increased osteopontin contributes to inhibition of bone mineralization in FGF23-deficient mice
Excessive FGF23 has been identified as a pivotal phosphaturic factor leading to renal phosphate-wasting, and the subsequent development of rickets and osteomalacia. In contrast, loss of FGF23 in mice (Fgf23(−/−)) leads to high serum phosphate, calcium and 1,25-vitamin-D levels resulting in early let...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937302/ https://ncbi.nlm.nih.gov/pubmed/24038141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2079 |
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