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Deletion of PTH Rescues Skeletal Abnormalities and High Osteopontin Levels in Klotho (−/−) Mice
Maintenance of normal mineral ion homeostasis is crucial for many biological activities, including proper mineralization of the skeleton. Parathyroid hormone (PTH), Klotho, and FGF23 have been shown to act as key regulators of serum calcium and phosphate homeostasis through a complex feedback mechan...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3355080/ https://ncbi.nlm.nih.gov/pubmed/22615584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002726 |
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