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Deletion of PTH Rescues Skeletal Abnormalities and High Osteopontin Levels in Klotho (−/−) Mice

Maintenance of normal mineral ion homeostasis is crucial for many biological activities, including proper mineralization of the skeleton. Parathyroid hormone (PTH), Klotho, and FGF23 have been shown to act as key regulators of serum calcium and phosphate homeostasis through a complex feedback mechan...

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Bibliografske podrobnosti
Main Authors: Yuan, Quan, Sato, Tadatoshi, Densmore, Michael, Saito, Hiroaki, Schüler, Christiane, Erben, Reinhold G., Lanske, Beate
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355080/
https://ncbi.nlm.nih.gov/pubmed/22615584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002726
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