Deletion of Zfp521 rescues the growth plate phenotype in a mouse model of Jansen metaphyseal chondrodysplasia

Jansen metaphyseal chondrodysplasia (JMC) is caused by a constitutively activating mutation of the parathyroid hormone (PTH)/PTH-related protein (PTHrP) receptor (PTHR1) and is characterized by widening of the metaphyses, reduction of long bone length, and short stature. A transgenic mouse expressin...

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Autores principales: Seriwatanachai, Dutmanee, Densmore, Michael J., Sato, Tadatoshi, Correa, Diego, Neff, Lynn, Baron, Roland, Lanske, Beate
Formato: Artigo
Lenguaje:Inglês
Publicado: Federation of American Societies for Experimental Biology 2011
Materias:
Research Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157684/
https://ncbi.nlm.nih.gov/pubmed/21642473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-183277
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