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PTH Ablation Ameliorates the Anomalies of Fgf23-Deficient Mice by Suppressing the Elevated Vitamin D and Calcium Levels
Fibroblast growth factor 23 (FGF23) is a key regulator of mineral ion homeostasis. Genetic ablation of Fgf23 in mice leads to severe biochemical disorders including elevated serum 1,25-dihydroxyvitamin D [1,25(OH)(2)D], hypercalcemia, hyperphosphatemia, and marked decreased PTH levels. Because PTH s...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Endocrine Society
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3199001/ https://ncbi.nlm.nih.gov/pubmed/21896668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1113 |
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