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Genetic Ablation of Vitamin D Activation Pathway Reverses Biochemical and Skeletal Anomalies in Fgf-23-Null Animals
Fibroblast growth factor-23 (FGF-23) is one of the circulating phosphaturic factors associated with renal phosphate wasting. Fgf-23(−/−) animals show extremely high serum levels of phosphate and 1,25-dihydroxyvitamin D(3), along with abnormal bone mineralization and soft tissue calcifications. To de...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Investigative Pathology
2006
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1762489/ https://ncbi.nlm.nih.gov/pubmed/17148678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060329 |
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