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Molecular interactions of FGF23 and PTH in phosphate regulation

Bone-derived fibroblast growth factor-23 (FGF23) plays an important role in systemic phosphate turnover. Increased FGF23 activity results in hypophosphatemic, while reduced activity is linked to hyperphosphatemic disorders. FGF23, together with klotho as co-factor, can activate FGF-receptors in its...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Lanske, Beate, Razzaque, Mohammed S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246422/
https://ncbi.nlm.nih.gov/pubmed/25427080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2014.316
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