Parathyroid hormone 1 receptor is essential to induce FGF23 production and maintain systemic mineral ion homeostasis

Parathyroid-hormone–type 1 receptor (PTH1R) is extensively expressed in key regulatory organs for systemic mineral ion homeostasis, including kidney and bone. We investigated the bone-specific functions of PTH1R in modulating mineral ion homeostasis by generating a novel mouse model in which PTH1R i...

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Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: Fan, Yi, Bi, Ruiye, Densmore, Michael J., Sato, Tadatoshi, Kobayashi, Tatsuya, Yuan, Quan, Zhou, Xuedong, Erben, Reinhold G., Lanske, Beate
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2016
Soggetti:
Research Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684518/
https://ncbi.nlm.nih.gov/pubmed/26428657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-278184
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