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Parathyroid hormone 1 receptor is essential to induce FGF23 production and maintain systemic mineral ion homeostasis

Parathyroid-hormone–type 1 receptor (PTH1R) is extensively expressed in key regulatory organs for systemic mineral ion homeostasis, including kidney and bone. We investigated the bone-specific functions of PTH1R in modulating mineral ion homeostasis by generating a novel mouse model in which PTH1R i...

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Bibliographische Detailangaben
Veröffentlicht in:FASEB J
Hauptverfasser: Fan, Yi, Bi, Ruiye, Densmore, Michael J., Sato, Tadatoshi, Kobayashi, Tatsuya, Yuan, Quan, Zhou, Xuedong, Erben, Reinhold G., Lanske, Beate
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684518/
https://ncbi.nlm.nih.gov/pubmed/26428657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-278184
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